Seroquel should typically be prescribed by having an initial dosage of 25 milligrams. Then advances in amounts of 25-50 mg on the 2nd and third day to a target dose range of 300 to 400 milligrams on a daily basis by the 4th day. More dosage adjustments should commonly occur at intervals of no less than two days, as a steady state for Seroquel with the typical patient would not be achieved for roughly 1-2 days.

In clinical trial databases tests were designed with estimated dosage amounts between 1200 mg and 9600 milligrams with zero deaths. Generally, reported indicators had been those due to an exaggeration of the drug's known pharmacological side effects, i.e. drowsiness and sedation, tachycardia as well as hypotension. One event, involving an approximated overdose of 9600 milligrams, had been linked with hypokalemia and first degree coronary heart block. There were very rare reports associated with overdosing on Seroquel producing loss of life or coma in post-marketing experience.

Side effects of a seroquel overdose might include: Rapid pulse (also known as tachycardia), which can raise the probability of stroke or heart attack, disturb the regular functionality of the heart as well as trigger sudden heart attack. A person who overdoses on Seroquel could have difficulty staying awake and feeling severe sleepiness. Fainting occurs when a person temporarily loses consciousness. A seroquel overdose can result in dizziness, which relates to emotions of some weakness, unsteadiness, faintness and wooziness. Fatigue is characterized by insufficient vitality or feeling of exhaustion during physical activities.

In the case of serious overdosage create and maintain an airway and assure sufficient oxygenation and ventilation. Stomach lavage and administration of activated charcoal along with a laxative should be considered. The chance of obtundation, seizure or dystonic reaction of the head as well as neck right after an overdose could generate a risk of aspiration with induced vomiting. Cardiovascular monitoring ought to get started promptly and ought to include ongoing electrocardiographic monitoring in order to detect possible arrhythmias.